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Review Natural and TGF-b induced CD4 CD25 regulatory T cells The spectrin tetramer is then able to capture and stabilize additional membrane interacting proteins, forming the characteristic profile of a polarized membrane domain, thus facilitating acquisition of proteins such as the basolateral Na-K ATPase. Natural and TGF-b–induced Foxp3+CD4+ CD25+ regulatory T cells are not mirror images of each other David A. Horwitz, Song Guo Zheng and J. Dixon Gray
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